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Therapeutic Expertise

Cannabinoid & Psychedelic

We are widely regarded as a market-leading CRO that specialises in cannabinoid and psychedelic clinical trials, serving global sponsors with high-quality, cost-effective and accelerated solutions.

Chronic painEpilepsy & MSDepression (MDD, PDD)PTSD & substance abuseAnorexia nervosa

Conducting clinical trials involving cannabinoids and psychedelics requires a meticulous approach to design, ethics, safety, and data collection, alongside collaboration with experts and adherence to regulatory guidelines.

We engage with principal investigators who have a deep understanding of the most suitable pre- and post-dose assessments, as well as access to a broad support network of psychotherapists, psychiatrists, and neurological experts.

Addressing common pain points in cannabinoid & psychedelic clinical trials

Regulatory barriers

Many countries still classify cannabinoids and psychedelics as controlled substances, making it difficult to obtain the permissions needed to conduct trials.

Cannabinoid & Psychedelic solution — Expert regulatory navigators

Our regulatory affairs specialists are experienced with global authorities on cannabinoid and psychedelic trials, facilitating efficient navigation and timely commencement.

Complexity of monitoring psychoactive effects

Quantifying and analysing the subjective experiences and potential long-term psychological effects is intricate.

Cannabinoid & Psychedelic solution — Innovative monitoring systems

We employ state-of-the-art digital tools and tailored patient surveys, ensuring comprehensive capture of psychoactive effects and long-term impacts.

Safety concerns

Given the psychoactive nature of these compounds, ensuring participant safety — especially in long-term studies — is paramount.

Cannabinoid & Psychedelic solution — Dedicated safety oversight

We have specialised safety monitoring boards with experts experienced in psychoactive substances, ensuring the utmost attention to participant safety.

Data management and interpretation

The multifaceted nature of data — psychological, physiological, and biochemical parameters — can be overwhelming.

Cannabinoid & Psychedelic solution — Advanced data management platforms

We use sophisticated data management systems capable of handling diverse, complex trial data, meticulously captured, stored, and analysed.

Blinding challenges

Due to the distinct, often strong effects of these substances, maintaining effective blinding in randomised controlled trials can be challenging.

Cannabinoid & Psychedelic solution — Rigorous blinding techniques

By leveraging advanced placebo designs and substances with similar non-psychoactive effects, we ensure the integrity of the blinding process.

Frequently asked questions

Cannabinoid & Psychedelic clinical trials — FAQs

Does iNGENū have experience with cannabinoid and psychedelic trials?
Yes — this is a core area of expertise. Australia has a supportive, well-defined regulatory pathway for cannabinoid and psychedelic-assisted therapy research, and we manage the scheduling, ethics and safety requirements end to end.
Are cannabinoid/psychedelic trial results usable for FDA submission?
Yes — studies are run to ICH-GCP and 21 CFR 312.120 so the data supports FDA and international regulatory filings.
How are the unique safety and blinding challenges handled?
With physician-led medical monitoring, validated functional-unblinding mitigations, and psychological support frameworks appropriate to psychedelic-assisted therapy protocols.

The iNGENū CRO difference

Australian expertise, direct FDA submission

We uniquely combine Australian expertise with direct FDA submission capabilities, offering a streamlined path for sponsors to achieve global approval. Trial data from Australia can be submitted directly to the FDA via our E-Gateway, eliminating the need for third-party intermediaries.

iNGENū takes a highly strategic and disciplined approach to clinical research, ensuring every dollar is directed toward generating meaningful outcomes — eliminating unnecessary costs while maintaining the highest scientific and regulatory standards across the Asia-Pacific region.

“We have been using iNGENū for a Phase 1, first-in-human trial of our investigational drug — medical writing, project management, clinical data management and full end-to-end execution and monitoring. We have been particularly impressed by the out-of-the-box creative solutions to speed up and reduce overheads during this clinical trial.”

Giles MossChief Executive Officer

Ready to discuss your Cannabinoid & Psychedelic clinical trial?

Talk to our team about how iNGENū CRO can accelerate your research.

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