Therapeutic Expertise

Anaesthesia & Pain Medicine

Our team understands the unique ethical considerations associated with conducting trials in patients with acute or chronic pain, and the importance of objective and subjective pain assessments, safety measures related to sedation and anaesthesia, and biomarkers of pain and inflammation.

Novel analgesicsAnaestheticsAdjunct therapies

Addressing common pain points in anaesthesia & pain medicine clinical trials

Patient recruitment and retention

Finding suitable patients who meet the specific criteria for anaesthesia and pain medicine trials, and keeping them engaged, poses significant hurdles.

Anaesthesia & Pain Medicine solution — Enhanced recruitment strategies

We leverage advanced patient databases to identify candidates rapidly and use patient-centric approaches such as flexible scheduling and remote monitoring to maximise retention.

Standardisation of pain measurement

Pain is subjective, and its measurement can vary between patients and evaluators, making consistent assessment difficult.

Anaesthesia & Pain Medicine solution — Standardisation

We implement standardised, validated pain assessment tools and train clinical staff on their consistent use and interpretation across all sites.

Placebo effects and blinding

Given the subjective nature of pain, placebo effects can be profound and effective blinding can be challenging.

Anaesthesia & Pain Medicine solution — Robust blinding methodologies

We design trials with robust blinding and use advanced statistical techniques to account for and analyse placebo responses.

Safety concerns

As anaesthesia and pain medications often have systemic effects, monitoring for adverse events and ensuring patient safety is critical.

Anaesthesia & Pain Medicine solution — Safety monitoring

Our dedicated safety board reviews data in real time using state-of-the-art monitoring systems, prioritising participant wellbeing and transparent communication.

Resources

Anaesthesia & Pain Medicine clinical trial resources

Neuropathic Pain

From pivotal endpoints to enhancing trial success.

Acute Pain

Evolving insights into acute pain diagnosis and treatments.

Fibromyalgia

Safety, efficacy, and regulatory considerations in fibromyalgia trials.

Post-Operative Pain

Pivotal endpoints, failures, and protocol enhancements.

Breakthrough Cancer Pain

Addressing clinical trial challenges from diagnosis to enhanced protocols.

Evidence & insights

Anaesthesia & Pain Medicine white papers

Open-access reports from our physicians and data science teams — free, no sign-in.

Frequently asked questions

Anaesthesia & Pain Medicine clinical trials — FAQs

What pain indications does iNGENū cover?

Acute pain, post-operative pain, breakthrough cancer pain, neuropathic pain, fibromyalgia and osteoarthritis, with validated pain endpoints and abuse-potential expertise where required.

Does iNGENū handle human abuse potential and thorough QT studies?

Yes — these specialised Phase 1 study types are part of our early-stage capability, run in FDA-audited units.

How does iNGENū manage the placebo and rater challenges in pain trials?

Through trained raters, enrichment designs where appropriate, and physician oversight to protect assay sensitivity.

The iNGENū CRO difference

Australian expertise, direct FDA submission

We uniquely combine Australian expertise with direct FDA submission capabilities, offering a streamlined path for sponsors to achieve global approval. Trial data from Australia can be submitted directly to the FDA via our E-Gateway, eliminating the need for third-party intermediaries.

iNGENū takes a highly strategic and disciplined approach to clinical research, ensuring every dollar is directed toward generating meaningful outcomes — eliminating unnecessary costs while maintaining the highest scientific and regulatory standards across the Asia-Pacific region.

“We have been using iNGENū for a Phase 1, first-in-human trial of our investigational drug — medical writing, project management, clinical data management and full end-to-end execution and monitoring. We have been particularly impressed by the out-of-the-box creative solutions to speed up and reduce overheads during this clinical trial.”

Giles MossChief Executive Officer

Ready to discuss your Anaesthesia & Pain Medicine clinical trial?

Talk to our team about how iNGENū CRO can accelerate your research.

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